Here's a sign of equality of the sexes!
Half of the cartoons on 4Kids TV (Fox) Saturday morning this season are primarily targeted towards girls!
Magical DoReMi (the anime Ojamajou Doremi)
Mew Mew Power (the anime Tokyo Mew Mew)
Winx Club (I think it's an Italian import)
I don't remember cartoons in the 80's ever being targeted towards girls. I grew up with shows like The Smurfs, with all of one or two female characters (depending on the season) and plenty of other shows with two or three token girls.
Now, one of those shows isn't continuing, though....